Organizing a cell’s genetic material from the sidelines
A tremendous amount of genetic material must be packed into the nucleus of every cell -- a tiny compartment. One of the biggest challenges in biology is to understand how certain regions of this highly packaged DNA can be called upon so that the genes encoded in them...
Obesity + aging linked to Alzheimer’s markers in the brain
A new study suggests that when a high-fat, high-sugar diet that leads to obesity is paired with normal aging, it may contribute to the development of Alzheimer's disease. In addition, researchers discovered that certain areas of the brain respond differently to risk...
New promise in search for simple, early test for Alzheimer’s disease
Researchers have found early evidence that tiny snippets of genetic material called microRNA may help with early detection of conditions such as Alzheimer's disease. read the full article
The odds of living to 110-plus level out — once you hit 105
The chances of reaching the ripe old age of 110 are within reach -- if you survive the perilous 90s and make it to 105 when death rates level out, according to a study of extremely old Italians. read the full article
Unraveling genetic risk factors for Alzheimer’s disease
The strongest genetic risk factor for Alzheimer's disease may impair the brain's ability to convert its primary fuel source into usable energy, finds a study of female mice. The research suggests therapeutic strategies that promote brain energy conversion in risk gene...
Treating Alzheimer’s with aspirin
A low-dose aspirin regimen may represent a new avenue for reducing Alzheimer's disease pathology, according to new research in a mouse model. The study identifies a new role for one of the most widely used medications in the world. read the full article
Expecting a stressful day may lower cognitive abilities throughout the day
There may be some truth to the saying 'getting up on the wrong side of the bed,' according to researchers who say starting your morning by focusing on how stressful your day will be may be harmful to your mindset throughout the day. read the full article
Feeling young could mean your brain is aging more slowly
While some people are young at heart, others feel older than their age -- and a recent study finds that this 'subjective age' may reflect brain aging. Researchers found that elderly people who feel younger than their age had a younger estimated brain age, compared...
Brain study paves way for therapy for common cause of dementia
Scientists have uncovered a potential approach to treat one of the commonest causes of dementia and stroke in older people. Studies with rats found the treatment can reverse changes in blood vessels in the brain associated with the condition, called cerebral small...
‘Skinny fat’ in older adults may predict dementia, Alzheimer’s risk
A first-of-its-kind study has found that 'skinny fat' -- the combination of low muscle mass and strength in the context of high fat mass -- may be an important predictor of cognitive performance in older adults. Using data from a series of community-based aging and...